SR 1664 - CAS 1338259-05-4
Catalog number: 1338259-05-4
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C33H29N3O5
Molecular Weight:
547.61
COA:
Inquire
Targets:
PPAR
Description:
SR 1664 is a PPARγ (peroxisome proliferator-activated receptor γ ) inhibitor. SR 1664 can block PPARγ by cyclin-dependent kinase 5 with an IC50 value of 80 nM and it does not exhibit agonist activity at the PPARγ receptor. Recent research shows that SR 1664 has anti-diabetic effects in obese mice.
Purity:
98%
Appearance:
white to beige Powder
Synonyms:
(S)-4'-((2,3-dimethyl-5-((1-(4-nitrophenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid
Solubility:
DMSO: soluble15 mg/mL, clear
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
antidiabetic activity
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
IIJDFXNUWZTHIM-NRFANRHFSA-N
InChI:
1S/C33H29N3O5/c1-20-22(3)35(19-23-8-10-25(11-9-23)28-6-4-5-7-29(28)33(38)39)31-17-14-26(18-30(20)31)32(37)34-21(2)24-12-15-27(16-13-24)36(40)41/h4-18,21H,19H2,1-3H3,(H,34,37)(H,38,39)/t21-/m0/s1
Canonical SMILES:
C[C@H](NC(C1=CC=C(N(CC2=CC=C(C3=CC=CC=C3C(O)=O)C=C2)C(C)=C4C)C4=C1)=O)C5=CC=C([N+]([O-])=O)C=C5
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related PPAR Products


Saroglitazar
(CAS: 495399-09-2)

Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity as a drug for the treatment...

CAS 87893-55-8 15-deoxy-Δ12,14-Prostaglandin J2

15-deoxy-Δ12,14-Prostaglandin J2
(CAS: 87893-55-8)

15-deoxy-Δ12,14-Prostaglandin J2 is a TRPA1 agonist and an endogenous PPARγ ligand that induces adipocyte differentiation in C3H10Y1/2 fibroblasts (EC50 = 7 μM)...

CAS 122320-73-4 Rosiglitazone

Rosiglitazone
(CAS: 122320-73-4)

Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipoc...

CAS 24136-23-0 Arhalofenate

Arhalofenate
(CAS: 24136-23-0)

Arhalofenateis, also known as JNJ-39659100 and MBX102, as an uricosuric agent it is a selective, partial PPAR-γ agonist.

CAS 476436-68-7 Naveglitazar

Naveglitazar
(CAS: 476436-68-7)

Naveglitazar is a Dual peroxisome proliferator-activated receptor gamma and alpha (PPARgamma and PPARalpha) agonist

CAS 223132-38-5 Inolitazone dihydrochloride

Inolitazone dihydrochloride
(CAS: 223132-38-5)

In vitro, the IC50 for growth inhibition is approximately 0.8 nM while anaplastic thyroid carcinoma (ATC) tumor growth was inhibited three- to fourfold in nude ...

CAS 810677-36-2 PPARα-MO-1

PPARα-MO-1
(CAS: 810677-36-2)

A potent PPARα modulator

ST247
(CAS: 1356497-91-0)

ST247 is a selective and inverse peroxisome proliferator-activated receptor (PPAR)β/δ agonist with IC 50 value of 19 nm, 10-fold more potent than GSK0660 with I...

Quick Inquiry

Verification code

Featured Items