Squalene-2,3-diol - CAS 14031-37-9
Catalog number: 14031-37-9
Not Intended for Therapeutic Use. For research use only.
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Squalene-2,3-diol is a natural triterpenoid found in the herbs of Amoora dasyclada.
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1.New acyclic secondary metabolites from the biologically active fraction of
Al-Massarani SM;El Gamal AA;Abd El Halim MF;Al-Said MS;Abdel-Kader MS;Basudan OA;Alqasoumi SI Saudi Pharm J. 2017 Jan;25(1):110-119. doi: 10.1016/j.jsps.2016.05.006. Epub 2016 May 24.
The total extract of ;Albizia lebbeck; flowers was examined ;in vivo; for its possible hepatoprotective activity in comparison with the standard drug silymarin at two doses. The higher dose expressed promising activity especially in reducing the levels of AST, ALT and bilirubin. Fractionation via liquid-liquid partition and reexamination of the fractions revealed that the ;n;-butanol fraction was the best in improving liver biochemical parameters followed by the ;n;-hexane fraction. However, serum lipid parameters were best improved with CHCl;3; fraction. The promising biological activity results initiated an intensive chromatographic purification of ;A. lebbeck; flowers fractions. Two compounds were identified from natural source for the first time, the acyclic farnesyl sesquiterpene glycoside1-O-[6-O-;α;-l-arabinopyranosyl-;β;-d-glucopyranoside]-(2;E;,6;E;-)-farnesol (;6;) and the squalene derivative 2,3-dihydroxy-2,3-dihydrosqualene (;9;), in addition to eight compounds reported here for the first time from the genus ;Albizia;; two benzyl glycosides, benzyl 1-O-;β;-d-glucopyranoside (;1;) and benzyl 6-O-;α;-l-arabinopyranosyl ;β;-d-glucopyranoside (;2;); three acyclic monoterpene glycosides, linalyl ;β;-d-glucopyranoside (;3;) and linalyl 6-O-;α;-l-arabinopyranosyl-;β;-d-glucopyranoside (;4;); (2;E;)-3,7-dimethylocta-2,6-dienoate-6-O-;α;-l arabinopyranosyl-;β;-d-glucopyranoside (;5;), two oligoglycosides, ;n;-hexyl-;α;-l arabinopyranosyl-(1 → 6)-;β;-d-glucopyranoside (creoside) (;7;) and ;n;-octyl ;α;-l-arabinopyranosyl-(1 → 6)-;β;-d-glucopyranoside (rhodiooctanoside) (;8;); and ethyl fructofuranoside (;10;).
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CAS 14031-37-9 Squalene-2,3-diol

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