|Molecular Formula||C10H17N2O13P3S (free acid)|
|Molecular Weight||498.2 (free acid)|
|Structure\Application||Phosphate modified Nucleotides|
|Description||Sp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable.|
|Purity||≥ 95% by HPLC|
|Synonyms||Thymidine- 5'- O- (1-thiotriphosphate), Sp-isomer|
Sp-2'-O-Me-CTP-α-S is a CTP analogue that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.
6-(1-MeBu)-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
Mant-GTPγS had lower affinities for Gαs and Gαi than GTPγS/GppNHp as assessed by inhibition of GTP hydrolysis of receptor-Gα fusion proteins. MANT-GTPγS was muc...
Rp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable.
ddTTP-α-S is used in mass spectrometric genotyping.
GTPαS can be accomplished by 50-thiophosphorylation of 7-methylguanosine in (MeO)3PO in the presence of 2,6-lutidine,12 followed by addition of tributylammonium...
ddUTP-α-S is used in mass spectrometric genotyping.