|Molecular Formula||C10H17N2O13P3S (free acid)|
|Molecular Weight||498.2 (free acid)|
|Structure\Application||Phosphate modified Nucleotides|
|Description||Sp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable.|
|Purity||≥ 95% by HPLC|
|Synonyms||Thymidine- 5'- O- (1-thiotriphosphate), Sp-isomer|
GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins.
6-cHe-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
ddATP-α-S is used in mass spectrometric genotyping.
Mant-GTPγS had lower affinities for Gαs and Gαi than GTPγS/GppNHp as assessed by inhibition of GTP hydrolysis of receptor-Gα fusion proteins. MANT-GTPγS was muc...
GTPγS is a stable G-protein-activating (GTP) analog. The physiological actions of GTPgammaS includestimulation of guanine nucleotide-binding proteins, phosphoin...
Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.
CDP-β-S is a CDP binding proteins regulator with a higher stability. It is used for characterization of CDP-responsive receptors, determination of their stereos...
Sp-2'-O-Me-CTP-α-S is a CTP analogue that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.