|Description||Sp-cAMPS-AM is a precursor of Sp-cAMPS, the PDE-resistant protein kinase A stimulator. Sp-cAMPS is released after metabolism of Sp-cAMPS-AM by esterases.|
|Purity||≥ 97% by HPLC for mixture of the axial and equatorial isomer|
|Synonyms||Adenosine- 3', 5'- monophosphorothioate acetoxymethyl ester, Sp- isomer|
cAMP-AM is a membrane-permeant precursor of cAMP, the second messenger. cAMP is released after permeation and metabolism of cAMP-AM by esterases, then it is met...
8-APT-cGMP is an isozyme-selective stimulator of cGMP-dependent protein kinase I a with a prenference for type I a over I by a factor of 200.
8-AET-cGMP is a ligand in affinity chromatography and can be modified with fluorophores or other markers.
Sp-6-AE-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethyl spacer, which can be used in affinity chromatography of...
c-di-2'-dGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
c[G(2',5')pS-A(3',5')pS], isomer 1 and i
(CAS: 1638242-56-4 / 1638243-00-1)
c[G(2',5')pS-A(3',5')pS] is an isomeric di-thiophosphate analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is resistant a...
Sp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chrom...
8-Br-PET-cGMP is a stimulator of isozymes I α and I β of cGMP-dependent protein kinase, which is used as an excellent cyclic nucleotide muscle relaxants.
8-Cl-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which is used for binding studies and precursor for further modifications with spacers o...
c-diIMP is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which is potentially used as an adjuvant for mucosal vaccination.
c-diGMP is a bacterial second messenger and a STING ligand.
Rp-8-Br-cAMPS is an analogue of the cAMP with a preference for type I of protein kinase A. Compared to Rp-cAMPS, it has more lipophilic and membrane-permeant pr...
2'-dcAMP is an analogue of cAMP, which is a protein kinase A inactive agent.
Sp-c-diAMPS is an analogue of c-diAMP, the bacterial second messenger.
8-AHA-cAMP is a selective cAMP analogue preferring site B of R I of cAMP-dependent protein kinase. It can be active to site A of R I and site B of R II combinin...
8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effe...
2'-TAMRA-AEC-cGMP is a fluorescent cGMP analogue (λexc555 nm, λem580 nm) that can be used for phosphodiesterase studies.