|Molecular Formula||C18H14BrN5O6PS · Na|
|Description||Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I α and I ß (cGMP agonist), which is used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases.|
|Purity||≥ 99% by HPLC|
|Synonyms||8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt|
8-AET-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxyl group immobilized on agarose by an aminoethylthio spacer, which can...
Rp,Sp-c-diAMPSS is an analogue of c-diAMP, the bacterial second messenger, which has higher stability. It can be used to study ligand-receptor interactions.
2'-dcAMP is an analogue of cAMP, which is a protein kinase A inactive agent.
8-Br-PET-cGMP is a stimulator of isozymes I α and I β of cGMP-dependent protein kinase, which is used as an excellent cyclic nucleotide muscle relaxants.
Rp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers.
cCMP-AM is a membrane-permeant and metabolically activatable prodrug of cCMP, the potential further second messenger. cCMP is released after permeation and meta...
8-AHA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucl...
4-MB-cCMP is an analogue of cCMP, the putative second messenger nucleotide and the main cellular metabolite of DB-cCMP. 4-MB-cCMP exhibits a partial activity of...
c[G(2',5')pA(3',5')p] / 2'3'-cGAMP
c[G(2',5')pA(3',5')p] was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. ...
Rp-5,6-DCl-cBIMPS is a phosphodiesterase-resistant regulator of cAMP-dependent protein kinase.
c-di-2'-d-2''-O-Me-AMP is an analogue of c-diAMP, the bacterial second messenger.
8-AHA-2-Cl-cAMP is a selective cAMP analogue that has a preference for side B I of PKA.
8-Biotin-11-c-diGMP is an analogue of c-diGMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatog...
8-CPT-cAMP-AM is a precursor of 8-CPT-cAMP, the PKA activator. 8-CPT-cAMP is released after the metabolism of 8-CPT-cAMP-AM by esterases.
Sp-2'-O-MB-cAMPS is a precursor ofSp-cAMPS, a PDE-resistant stimulator of protein kinase A. Sp-cAMPS and butyrate are released after the metabolism of Sp-2'-O-M...
Rp-8-Br-2'-O-MB-cAMPS is a precursor of Rp-8-Br-cAMPS, the protein kinase A inhibitor. Rp-8-Br-cAMPS and butyrate are released after the metabolism of Rp-8-Br-2...
2'-AEC-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers.
c-di-2'-dAMP is an analogue of c-diAMP, the bacterial second messenger.
2-Cl-cAMP is a selective cAMP analogue preferring the B sites of both protein kinase A type I and II.