|Description||Sp-8-Br-cAMPS-AM is a PDE-resistant precursor of Sp-8-Br-cAMPS, the protein kinase A stimulator. The active analogue is released after the metabolism of Sp-8-Br-cAMPS-AM by esterases.|
|Purity||≥ 97% by HPLC for mixture of the axial and equatorial isomer|
|Synonyms||8- Bromoadenosine- 3', 5'- monophosphorothioate, acetoxymethyl ester, Sp- isomer ( Sp-8-Br-cAMPS-AM )|
8-AHA-2-Cl-cAMP is a selective cAMP analogue that has a preference for side B I of PKA.
8-OH-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It can be used in patc...
8,8'-Di-Br-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used for binding studies and for further modifications with spacers o...
6-Bn-cAMP is a selective stimulator of cAMP-dependent protein kinase which does not activate Epac. Compared to cAMP, it has superior stability against PDE, este...
2',2''-Di-AHC-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of la...
Sp-6-AH-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and oth...
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] / Rp,Rp
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] is a synthetic cyclic dinucleotide with higher stability resisting degradation by phosphodiesterases. It has improved binding a...
8-AEA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucl...
8-pCPT-2'-O-Me-cAMP-AM is a precursor of 8-pCPT-2'-O-Me-cAMP, the specific Epac agonist. 8-pCPT-2'-O-Me-cAMP is released after the metabolism of 8-pCPT-2'-O-Me-...
8-Br-cGMP-AM is a precursor of 8-Br-cGMP, the PKG activator. The polar active analogue is released after the metabolism of 8-Br-cGMP-AM by esterases.
2'-O-MB-cCMP is a precursor and biologically inactive analogue of cCMP, the putative second messenger nucleotide. cCMP would be released when 2'-O-MB-cCMP is me...
2'-AHC-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling...
2-AH-cGMP-Agarose is the second messenger cGMP immobilized on agarose by an aminohexyl spacer which can be used in affinity chromatography of cyclic nucleotide-...
Rp,Rp-c-diGMPSS is an analogue of c-diGMP, the bacterial second messenger, with improved stability. It can be used to study ligand-receptor interactions.
Sp-5,6-DCl-cBIMPS is a selective stimulator of cAMP- dependent protein kinases preferrring site B of type II isozyme. It is superior to dibutyryl cAMP or 8-CPT-...
6-Phe-cAMP is a selective stimulator of protein kinase A preferring site A of both isozymes.
8-AET-cGMP-Agarose is the second messenger cGMP immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucle...
8-ADOA-cAMP is a selective and hydrophilic cAMP analogue, which is used as a ligand in affinity chromatography and can be modified with fluorophores.