|Description||Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 8-AHA-cAMP.|
|Purity||≥ 98% by HPLC|
|Synonyms||8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer|
Sp-cAMPS, sodium salt
Sp-cAMPS is an activator of protein kinase A (cAMP agonist). It exhibits high resistance against cyclic nucleotide phosphodiesterases and membrane permeability ...
Sp-8-pCPT-2'-O-Me-cAMPS is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which is inactive for protein kinase A. It is much more li...
Sp-5,6-DCl-cBIMPS is a selective stimulator of cAMP- dependent protein kinases preferrring site B of type II isozyme. It is superior to dibutyryl cAMP or 8-CPT-...
6-AE-cAMP is often used as a ligand for affinity chromatography of cAMP and cGMP binding proteins.
Sp-8-PIP-cAMPS is a selective cAMP analogue with a preference for site B of protein kinase A type II.
8-N3-cAMP is an analogue of cAMP binding proteins used for photoaffinity labelling.
8-OH-cAMP is a polar analogue of cAMP used for the study of extracellular cAMP receptors. When applied by patch clamp techniques, 8-OH-cAMP remains trapped insi...
8-Br-2'-O-Me-cGMP is an analogue of cGMP that does not activate both protein kinase G and Epac. It is often used as an inactive control versus 8-Br-cGMP.
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] / Rp,Rp
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] is a synthetic cyclic dinucleotide with higher stability resisting degradation by phosphodiesterases. It has improved binding a...
Rp-8-Cl-cAMPS is a selective and competitive inhibitor of protein kinase A (cAMP antagonist) preferring type I of protein kinase A. It inhibits mammalian cyclic...
2'-AHC-cGMP is a cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
c[G(2',5')p-2'-dA(3',5')p] is a 2'-deoxy analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING stimulator, which can be...
6-Bn-cAMP is a selective stimulator of cAMP-dependent protein kinase which does not activate Epac. Compared to cAMP, it has superior stability against PDE, este...
EtOH-NH-Agarose is the agarose gel without nucleotide immobilized on it, which can be used as negative control in affinity chromatography experiments.
c-diGMP is a bacterial second messenger and a STING ligand.
8-BT-cAMP is a selective activator of cAMP-dependent protein kinase. Compared to cAMP, it has superior stability and membrane permeability.