|Description||Sp-6-AE-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others.|
2'-O-Me-cGMP is a polar analogue of cGMP that activate neither protein kinase G nor Epac. It exhibits an inactive effect in patch clamp applications and can be ...
2',2''-Di-c-didAMP is an analogue of c-diAMP, the bacterial second messenger.
Sp-cAMPS-AM is a precursor of Sp-cAMPS, the PDE-resistant protein kinase A stimulator. Sp-cAMPS is released after metabolism of Sp-cAMPS-AM by esterases.
Sp-2'-AHC-cGMPS is a PDE-stable cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
2'-O-Me-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I ...
c[G(2',5')p-2'-dA(3',5')p] is a 2'-deoxy analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING stimulator, which can be...
8-Br-cAMP-AM is a precursor of the PKA activator 8-Br-cAMP. The polar active analogue is released after metabolism of 8-Br-cAMP-AM by esterases.
6-Phe-cAMP is a selective stimulator of protein kinase A preferring site A of both isozymes.
6-Bnz-cAMP-AM is a precursor of 6-Bnz-cAMP, the specific PKA agonist, which can be used as an Epac-negative control. 6-Bnz-cAMP is released after the metabolism...
2'-NH2-cAMP is often used in affinity chromatography of cAMP and cGMP binding proteins for its amino group used as a ligand, which do not require an intact 2'-O...
8-CPT-cAMP-AM is a precursor of 8-CPT-cAMP, the PKA activator. 8-CPT-cAMP is released after the metabolism of 8-CPT-cAMP-AM by esterases.
Rp-2'-AHC-cGMPS is a PDE-stable cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
Sp-c-diGMPS is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
c-hexaAMP is a novel bacterial second messengers involved in the Type III CRISPR-Cas-associated detection and degradation of invasive genetic elements in many p...
6-Bn-cAMP is a selective stimulator of cAMP-dependent protein kinase which does not activate Epac. Compared to cAMP, it has superior stability against PDE, este...
6-AE-cAMP is often used as a ligand for affinity chromatography of cAMP and cGMP binding proteins.