|Molecular Formula||C12H10Cl2N2O5PS · Na|
|Description||Sp-5,6-DCl-cBIMPS is a selective stimulator of cAMP- dependent protein kinases preferrring site B of type II isozyme. It is superior to dibutyryl cAMP or 8-CPT-cAMP in stability, membrane permeability and potency.|
|Purity||≥ 99% by HPLC|
|Synonyms||5, 6- Dichlorobenzimidazole riboside- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt|
8-Br-cGMP-AM is a precursor of 8-Br-cGMP, the PKG activator. The polar active analogue is released after the metabolism of 8-Br-cGMP-AM by esterases.
Sp-cAMPS, triethyl ammonium salt
Sp-cAMPS is a stimulator of protein kinase A, the cAMP agonist. It has higher resistance against cyclic nucleotide phosphodiesterases compared to dibutyryl- or ...
Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control.
Rp-2'-AHC-cAMPS is an analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures su...
8-MA-cAMP is a selective cAMP analogue that has affinity to site B of protein kinase A type I and II. Site A activity is developed when 8-MA-cAMP acts synergist...
8-AHA-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer, which can...
Sp-2'-AEC-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chroma...
Rp-8-AEA-cAMPS-Agarose is the metabolically stable protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in...
DB-cAMP is a membrane-permeant activator of protein kinase A, the cAMP agonist.
8-HA-cAMP is a selective analogue of cAMP preferring site B of PKA I. It has high membrane permeability and superior stability towards phosphodiesterases.
c[A(2',5')pG(2',5')p] / 2'2'-cGAMP
c[A(2',5')pG(2',5')p] is a cyclic dinucleotide analogue of c[G(2',5')pA(3',5')p], the metazoan second messenger and STING activator. It can bind the signalling ...
2'-AHC-cAMP-Agarose is the protein kinase A activator cAMP immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography...
Rp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG inhibitor Rp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chrom...
Sp-6-AH-cAMPS-Agarose is the Sp-cAMPS immobilized on agarose by an aminohexyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsi...
cGMP-AM is a precursor of cGMP, the second messenger. The polar active analogue is released after the metabolism of cGMP-AM by esterases.
DB-cCMP is a membrane-permeant prodrug of cCMP, the potential further second messenger.
8-Biotin-11-c-diAMP is an analogue of c-diAMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatog...