|Molecular Formula||C11H18N5O13P3S (free acid)|
|Molecular Weight||553.3 (free acid)|
|Structure\Application||Phosphate modified Nucleotides|
|Description||Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.|
|Purity||≥ 95% by HPLC|
|Synonyms||2'- O- Methylguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt|
ATPγS is an agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, used as a reagent in...
Sp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable.
MANT-GppNHp bind to G alpha(i)-proteins with low affinity and are ineffective at activating G alpha. Besides, MANT-GppNHp constitutes a novel class of potent co...
ddGTP-α-S is used in mass spectrometric genotyping.
GDPβS has been found to exhibit activities as an inhibitor of G-coupled protein.
6-PhEt-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
6-Phe-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).