|Molecular Formula||C11H18N5O13P3S (free acid)|
|Molecular Weight||553.3 (free acid)|
|Structure\Application||Phosphate modified Nucleotides|
|Description||Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.|
|Purity||≥ 95% by HPLC|
|Synonyms||2'- O- Methylguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt|
Rp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable.
6-(1-MeBu)-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
DMNPE-caged ATP is a nucleotide analogue of ATP which esterified with a blocking group. It blocks ATP-sensitive K channels in cardiac muscle.
GpCpp is an analogue of GTP and could be used as a stabilizer in some microtubule<br/>cryoelectron microscopy studies.
6-Phe-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
GppNHp - Trisodium salt
The trisodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins.
ddGTP-α-S is used in mass spectrometric genotyping.
6-Fu-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach).
Sp-2'-O-Me-CTP-α-S is a CTP analogue that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.