|Molecular Formula||C11H18N5O13P3S (free acid)|
|Molecular Weight||553.3 (free acid)|
|Structure\Application||Phosphate modified Nucleotides|
|Description||Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA.|
|Purity||≥ 95% by HPLC|
|Synonyms||2'- O- Methylguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt|
ddATP-α-S is used in mass spectrometric genotyping.
Mant-GTPγS had lower affinities for Gαs and Gαi than GTPγS/GppNHp as assessed by inhibition of GTP hydrolysis of receptor-Gα fusion proteins. MANT-GTPγS was muc...
GDPβS has been found to exhibit activities as an inhibitor of G-coupled protein.
ATPγS is an agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, used as a reagent in...