|Description||SP 100030 is a potent dual inhibitor of NF-κB and AP-1 transcriptional activity (IC50 = 50 nM). SP 100030 blocks production of IL-2, IL-8 and TNF-α from Jurkat T cells. It inhibits cytokine production selectively in T cells and exhibits minimal inhibitory effects on cytokine production in other cell types.|
|Brife Description||NF-κB and AP-1 transcriptional activity inhibitor|
|Purity||≥99% by HPLC|
|Synonyms||SP-100030; SP 100030; SP100030; N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide|
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