SP 100030 - CAS 154563-54-9
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C14H5ClF9N3O
Molecular Weight:
437.65
COA:
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Targets:
NF-κB
Description:
SP 100030 is a potent dual inhibitor of NF-κB and AP-1 transcriptional activity (IC50 = 50 nM). SP 100030 blocks production of IL-2, IL-8 and TNF-α from Jurkat T cells. It inhibits cytokine production selectively in T cells and exhibits minimal inhibitory effects on cytokine production in other cell types.
Brife Description:
NF-κB and AP-1 transcriptional activity inhibitor
Purity:
≥99% by HPLC
Synonyms:
SP-100030; SP 100030; SP100030; N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide
MSDS:
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InChIKey:
GHMKQBWHPQMXSH-UHFFFAOYSA-N
InChI:
InChI=1S/C14H5ClF9N3O/c15-11-25-4-8(9(27-11)14(22,23)24)10(28)26-7-2-5(12(16,17)18)1-6(3-7)13(19,20)21/h1-4H,(H,26,28)
Canonical SMILES:
C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=CN=C(N=C2C(F)(F)F)Cl)C(F)(F)F
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Chemical Structure

CAS 154563-54-9 SP 100030

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