|Description||Sitamaquine tosylate is a dose-dependent and orally bioactive inhibitor of complex II (succinate dehydrogenase or SDH) of the respiratory chain in digitonin-permeabilized promastigotes. Sitamaquine has the potential for the treatment of life-threatening visceral leishmaniasis (VL) caused by Leishmania donovani (EC50 value 19.8 μM for L. donovani promastigotes in vitro).|
|Brife Description||complex II (succinate dehydrogenase or SDH) inhibitor|
|Related CAS||57695-04-2 (free base)|
|Synonyms||WR6026 tosylate; WR-6026 tosylate; WR 6026 tosylate|
AT-4930 is a bio-active molecular, but detailed information has not been published yet.
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