Silodosin - CAS 160970-54-7
Catalog number: 160970-54-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
Adrenergic Receptor
Silodosin shows high selectivity for the alpha(1A)-AR subtype.
KMD-3213; KMD3213; KMD 3213; KAD 3213; KAD 3213; KAD3213; Silodosin. trade names Rapaflo, Silodyx, Rapilif, Silodal, Urief, Urorec.
Canonical SMILES:
1.Relative cytotoxic potencies and cell death mechanisms of α1 -adrenoceptor antagonists in prostate cancer cell lines.
Forbes A1, Anoopkumar-Dukie S2, Chess-Williams R1, McDermott C1. Prostate. 2016 Feb 16. doi: 10.1002/pros.23167. [Epub ahead of print]
BACKGROUND: Some α1 -adrenoceptor antagonists possess anti-cancer actions that are independent of α1 -adrenoceptors and the aim of these studies was to assess the relative cytotoxic potencies of α1 -adrenoceptor antagonists and the mechanisms involved in these actions.
2.A randomized, comparative, open-label study of efficacy and tolerability of alfuzosin, tamsulosin and silodosin in benign prostatic hyperplasia.
Manjunatha R1, Pundarikaksha HP1, Madhusudhana HR2, Amarkumar J2, Hanumantharaju BK2. Indian J Pharmacol. 2016 Mar-Apr;48(2):134-40. doi: 10.4103/0253-7613.178825.
OBJECTIVES: Benign prostatic hyperplasia (BPH) is a common and progressive disease affecting elderly males, often associated with lower urinary tract symptoms (LUTS). α1-blockers are the mainstay in symptomatic therapy of BPH. Because of their greater uroselectivity and minimal hemodynamic effects, alfuzosin, tamsulosin, and silodosin are generally preferred. The aim of this study was to compare the efficacy and tolerability of alfuzosin, tamsulosin, and silodosin in patients with BPH and LUTS.
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CAS 160970-54-7 Silodosin

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