|Description||Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway. Sennoside B is therefore of potential utility in the treatment of proliferative diseases in which PDGF signaling plays a central role.|
|Synonyms||GLYSENNIDE; (9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid; SENNOSIDE B; PURSENNIDE; SENNOSIDE B 96.5+%; Sennoside B std.; 9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-; (9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid|
2-Carbamoyl-3-hydroxy-1,4-naphthoquinone is a natural quinonoid compound found in several plants.
Shikonin belongs naphthoquinone isolated from Arnebia sp. It is used as an anti-inflammatory treatment in traditional chinese medicine (TCM). It inhibits chemok...
Tanshinone IIB isolated from the roots of Salvia miltiorrhiza. It inhibits the uptake of digoxin and vinblastine in membrane vesicles containing PgP or MRP1, mo...
Dimethylacrylshikonin usually can be found in the roots of Lithosperraum erythrorhizon Sieb. et Zucc. Injection of Dimethylacrylshikonin combined with IR treatm...
Rhein is a natural anthraquinone compound isolated from the root of Rheum palmatum L. Rhein exhibits the activities of anti-inflammatory, antitumor and antioxid...
Prerubialatin is a natural compound isolated from the herbs of Rubia cordifolia, being a precursor of rubialatins A and B.
4,9-Dihydroxy-alpha-lapachone isolated from the herbs of Catalpa ovata.
Dihydroisotanshinone II is a natural compound isolated from the roots of Salvia miltiorrhiza.
Pseudohypericin, which can be found in the herbs of Hypericum perforatum L, is implicated in the antidepressant efficacy of St. John's wort.
Torososide A is a natural anthraquinone found in the leaves of Cassia torosa.
Source from herbs of Rubia cordifolia L. Purpurin is a novel specific inhibitor of Adipocyte-derived leucine aminopeptidase and could be developed as a new anti...
9-Methoxy-α-lapachone isolated from the stems of Catalpa ovata.
Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway. Senno...
Floribundone 1 is a natural anthraquinone found in the herbs of Senna septemtrionalis.
Horminone isolated from the herbs of Salvia japonica Thunb. It may inhibit the initial steps of protein synthesis.
Rubioncolin C, also called as 1-Hydroxy-3-(3-methyl-2-butenyl)-4-[(1,4-dihydro-1,4-dioxonaphthalen)-2-yl]naphthalene-2-carboxylic acid methyl ester, is a natura...
Thymoquinone is a natural compound isolated from the seeds of N. sativa. Thymoquinone exhibits anti-inflammatory and anticancer effects. It inhibits the growth ...