|Description||Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway. Sennoside B is therefore of potential utility in the treatment of proliferative diseases in which PDGF signaling plays a central role.|
|Synonyms||GLYSENNIDE; (9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid; SENNOSIDE B; PURSENNIDE; SENNOSIDE B 96.5+%; Sennoside B std.; 9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-; (9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid|
Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells.
Questin is extracted from the seeds of Cassia obtusifolia. It is a Cdc25B phosphatase inhibitor with the IC50 value of 34 microg/mL. It is also a promising inhi...
Rhein is a natural anthraquinone compound isolated from the root of Rheum palmatum L. Rhein exhibits the activities of anti-inflammatory, antitumor and antioxid...
Source from roots of Lithosperraum erythrorhizon Sieb. et Zucc.
alpha-Tocopherolquinone isolated from the herbs of Isodon adenantha. It has antioxidant effect, which can inhibit lipid peroxidation and reduce cell division in...
Damnacanthal isolated from the fruit of Morinda citrifolia Linn.
Shikonin belongs naphthoquinone isolated from Arnebia sp. It is used as an anti-inflammatory treatment in traditional chinese medicine (TCM). It inhibits chemok...