|Description||Selinexor is a potent and selective inhibitor of chromosome region maintenance 1 protein/exportin 1 (CRM1/XPO1). Selinexor was studied to show in vivo anti-leukaemic efficacy against T-ALL and acute myeloid leukaemia (AML) cells.|
|B0084-463408||50 mg||$298||In stock|
|Synonyms||KPT-330; KPT 330; (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide|
Rabies Virus Glycoprotein, a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein, is only structural protein of the virus that induc...
VU 0463271 is a potent and selective inhibitor of KCC2, which is a neuronal K-Cl cotransporter (IC50 = 61 nM). VU 0463271 exhibits >100-fold selectivity versus ...
AS1949490 has been found to be a selective SHIP2 phosphatase inhibitor and show antidiabetic activities.
NSC-601980 analog is the analog of the NSC601980, which shows antitumor activity in the yeast screening experiment.
D-erythro-Sphingosine is a natural isomer of sphingosine and acts as an inhibitor of protein kinase C and calmodulin-dependent enzymes with no effects on protei...
DL-AP4 has been found to be a broad spectrum EAA ligand as well as an NMDA glutamate receptor antagonist.
Picloxydine, a heterocyclic biguanide, has antibacterial and antiplaque properties. In vitro studies have shown that the antibacterial<br/>properties of chlorhe...
Biotinyl-phenylboronic acid is the functionalized arylboronic acid of biotin used for palladium-catalyzed oxidative Heck reaction to protein-bound alkenes and S...
SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibit...
Leflunomideinhibits the reproduction of rapidly dividing cells by inhbiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH).
Vigabatrin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transa...
MS 15203 is a potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic mem...
CGP 37157 is a a selective sodium-calcium exchanger inhibitor with IC50 value of 0.36 μM in isolated mitochondria. It does not affect channels, exchangers, or A...
Cyhalofop(Cyhalofop acid) is a recently registered herbicide from the aryloxyphenoxy propionate group in India to control a wide range of grass weed species at ...
Astragaloside III is a saponin found in the root of Astragalus membranaceus (Fisch.) Bunge, which is known as huáng qí in Traditional Chinese Medicine. It has c...
BMS-505130 is a selective serotonin transport inhibitor with Ki of 0.18 nM. Ki value for binding to the norepinephrine is 4.6 mM and for dopamine transporters i...
OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavengi...
Meclofenoxate (Lucidril), also known as centrophenoxine, is a drug used to treat the symptoms of senile dementia and Alzheimer's disease. It is an ester of dime...
The deuterium labeled β-Apo-13-carotenone which is an antagonist of RXRα.