|Description||SCH 336 is a potent and selective CB2 receptor inverse agonist (Ki = 1.8 nM, EC50 = 2 nM) with 100-fold selectivity over CB1. SCH 336 has been shown to increase forskolin stimulated cAMP accumulation in CHO cells expressing human CB2 receptors. It inhibits leukocyte migration in a murine model of delayed-type hypersensitivity and suppresses antigen-induced lung eosinophilia in a mouse allergy model.|
|Brife Description||CB2 receptor inverse agonist|
|Purity||≥98% by HPLC|
|Synonyms||SCH-336; SCH 336; SCH336. N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide|
L-768242, an indole derivative, has been found to be a CB2 receptor agonist and was once studied to exhibit anti-nociceptive and antihyperalgesic activities in ...
JTE 907 is a highly selective cannabinoid CB2 receptor inverse agonist and has been found to exhibit anti-inflammatory properties.
AM 6545 has been found to be a CB1 antagonist and could probably be used as an appetite suppressant.
AM 2232, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor, with Ki values of 0.28 and 1.48 nM for th...
Levonantrado is a synthetic cannabinoid analog of dronabinol developed by Pfizer in the 1980s. Levonantrado is around 30x more potent than THC, and exhibits ant...
MDA 19, a benzohydrazide derivative, has been found to be a CB2 receptor agonist and could be useful in reducting the Attenuates tactile allodynia of rats. IC50...
Palmitoylethanolamide is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. It is a weak ligand of the cannabinoid 1 (CB1) and cannab...
ZCZ 011 is a cannabinoid CB1 receptor positive allosteric modulator (PAM) which augments the binding of the CB1 orthosteric agonists CP55940 (pEC50 value 6.90) ...