|Targets||Stearoyl-CoA Desaturase (SCD)|
|Description||SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays >100 fold selectivity over Δ5 and Δ9 desaturases (IC50 >200 μM in vitro). SC 26196 completely inhibits the conversion of linoleic acid to arachidonic acid (AA). It exhibits anti-inflammatory properties in a mouse edema model.|
|Brife Description||Δ6 desaturase inhibitor|
|Purity||≥98% by HPLC|
|Synonyms||α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile; PF-o6341724; FT-0674530|
MK-8245 Trifluoroacetate, a phenoxy piperidine isoxazole derivative, is a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor that has the potential for trea...
A939572 is a effective and highly selective cell-permeable inhibitor of SCD1(stearoyl-CoA desaturase 1) which could be mediated by hormonal and dietary actions....
SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays >100 fold selectivity over Δ5 and Δ9 desaturases (IC50 >200 μM in vitro)....
A 939572 is a potent and selective inhibitor of stearoyl-CoA desaturase 1 (SCD1) (IC50 = 0.4 nM). It suppresses proliferation of squamous cell, and induces apop...
MK-8245 is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-di...
PluriSln 1 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1). It is useful for eliminating undifferentiated human pluripotent stem cells (hPSCs) from culture ...