SB-408124 (Hydrochloride) - CAS 1431697-90-3
Catalog number: 1431697-90-3
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C19H19ClF2N4O
Molecular Weight:
392.84
COA:
Inquire
Targets:
Orexin Receptor (OX Receptor)
Description:
SB-408124 (Hydrochloride) is the hydrochloride salt form of SB-408124. SB-408124 is a selective antagonist of OX1 (for human OX1 Kb= 21.7nM; for human OX2 Kb=1405nM). In vivo: after oral administration it moderates Orexin-A blocking the vasopressin (VP) l
Appearance:
White to gray solid
Synonyms:
1-(6,8-difluoro-2-methylquinolin-4-yl)-3-[4-(dimethylamino)phenyl]urea;hydrochlorideSB-408124 (Hydrochloride)1431697-90-3C19H18F2N4O.ClH3024AHCS-1073; HY-76612; W-5807; SB-408124 (Hydrochloride); CS 1073; HY 76612; W 5807; SB 408124 (Hydrochloride); CS1073; HY76612; W5807; SB408124 (Hydrochloride);1-(6,8-Difluoro-2-methylquinolin-4-yl)-3-(4-(dimethylamino)phenyl)urea hydrochloride
Solubility:
Soluble in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -43℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
InChIKey:
DIHXPSGMLOETTI-UHFFFAOYSA-N
InChI:
1S/C19H18F2N4O.ClH/c1-11-8-17(15-9-12(20)10-16(21)18(15)22-11)24-19(26)23-13-4-6-14(7-5-13)25(2)3;/h4-10H,1-3H3,(H2,22,23,24,26);1H
Canonical SMILES:
CC1=NC2=C(C=C(C=C2C(=C1)NC(=O)NC3=CC=C(C=C3)N(C)C)F)F.Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Orexin Receptor (OX Receptor) Products


CAS 1369764-02-2 Lemborexant

Lemborexant
(CAS: 1369764-02-2)

Lemborexant, an orexin OX1/OX2 receptors antagonist, has been found to be effective against insomnia and is just planed a Phase III trail by Eisai.

JNJ-10397049
(CAS: 708275-58-5)

JNJ-10397049 is a selective orexin-2 receptor (OX2) antagonist. pIC50 is 7.4 for chimeric OX2 receptors/ pKB values are 5.9 for OX1 and 8.5 for OX2 receptors re...

CAS 205640-90-0 Orexin A (human, rat, mouse)

Orexin A (human, rat, mouse)
(CAS: 205640-90-0)

An orexin receptors agonist. It can stimulate feeding following central administration.

CAS 249889-64-3 SB-334867

SB-334867
(CAS: 249889-64-3)

SB-334867, with sedative and anorectic effects, it is the first non-peptide selective antagonist of orexin receptor subtype OX1 (pKb= 7.2) with 50 -fold selecti...

CAS 1373765-19-5 IPSU

IPSU
(CAS: 1373765-19-5)

IPSU is a selective, orally available and brain penetrant OX2 receptor antagonist (pKi= 7.85) with 6-fold selectivity over OX1 receptors.

CAS 871224-64-5 Almorexant

Almorexant
(CAS: 871224-64-5)

Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and ...

CAS 343268-91-7 OXA (17-33)

OXA (17-33)
(CAS: 343268-91-7)

OXA (17-33) is a peptide orexin OX1 receptor agonist with EC50 value of 8.29 nM. It is a drug candidate for the treatment of heart failure and hypertension.

CAS 380899-24-1 SB-649868

SB-649868
(CAS: 380899-24-1)

SB-649868 is a novel, orally active dual orexin receptor antagonist of orexin(OX)1 and OX2 receptor (pKi=9.4 and 9.5 at the OX1 and OX2 receptor, respectively),...

Quick Inquiry

Verification code

Featured Items