Sarmentosin - CAS 71933-54-5
Catalog number: 71933-54-5
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
Chemical Family:
Other Natural Compounds
Sarmentosin isolated from the herb of Sedum sarmetosum Bunge. It shows a good effect in lowering serum glutamate-pyruvate transaminase and lowering the SGPT level of patients suffering from chronic viral hepatitis.
Publictions citing BOC Sciences Products
  • >> More
Sarmentosin shows a suppressive effect on cell-mediated immune responses in mice.
Quality Standard:
Enterprise Standard
1.Prolyl endopeptidase inhibitors from the underground part of Rhodiola sacra S. H. Fu.
Fan W;Tezuka Y;Komatsu K;Namba T;Kadota S Biol Pharm Bull. 1999 Feb;22(2):157-61.
Prolyl endopeptidase (PEP, EC is an enzyme which plays a role in the metabolism of proline-containing neuropeptides, e.g., vasopressin, substance P and thyrotropin-releasing hormone (TRH), which have been suggested to be involved in learning and memory processes. In our systematic screening for PEP inhibitors from traditional Chinese medicines, we found that MeOH extract from the underground part of Rhodiola sacra S. H. Fu shows significant inhibitory activity against PEP from Flavobacterium meningosepticum. Examination of the constituents of the extract resulted in the isolation of nineteen known compounds, identified as hydroquinone (1), 4-hydroxybenzoic acid (2), caffeic acid (3), 4-hydroxycinnamic acid (4), suberic acid (5), protocatechuic acid (6), gallic acid (7), (-)-epigallocatechin 3-O-gallate (8), 2-phenylethyl beta-D-glucopyranoside (9), 3-O-galloylepigallocatechin-(4beta-->8)-epigallocatechin+ ++ 3-O-gallate (10), 2-phenylethyl alpha-L-arabinopyranosyl-(1-->6)-beta-D-glucopyranoside (11), sacranoside A (12), beta-D-glucopyranosyl 4-hydroxybenzoate (13), rhodiocyanoside A (14), rhodiooctanoside (15), sarmentosin (16), heterodendrin (17), arbutin (18) and 4-O-(beta-D-glucopyranosyl)-gallic acid (19).
2.Hepatoprotective effects of Sedum sarmentosum on D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure.
Lian LH;Jin X;Wu YL;Cai XF;Lee JJ;Nan JX J Pharmacol Sci. 2010;114(2):147-57. Epub 2010 Sep 11.
The hepatoprotective effects of sarmentosin-containing extracts of Sedum sarmentosum (SS) in D-galactosamine (D-GalN) / lipopolysaccharide (LPS)-induced fulminant hepatic failure mouse model. Pretreatment with SS markedly protected mice from lethal liver injury, which has known to be associated with an abrupt elevation of serum tumor necrosis factor (TNF)-α level. Indeed, SS significantly blocked the elevation of TNF-α and alanine aminotransferase and aspartate aminotransferase as well. SS also remarkably reduced number of apoptotic hepatocytes and DNA fragmentation in the liver, which correlated with blockade of caspase-3 activation. In addition, SS suppressed the increased expression of toll-like receptor 4 (TLR4). The activation of c-Jun NH(2)-terminal kinase, extracellular signal-regulated kinase, and p38 induced by D-GalN/LPS was also significantly suppressed by SS treatment. Furthermore, SS significantly inhibited the activation of nuclear factor-κB.
3.Diversification of an ancient theme: hydroxynitrile glucosides.
Bjarnholt N;Rook F;Motawia MS;Cornett C;Jørgensen C;Olsen CE;Jaroszewski JW;Bak S;Møller BL Phytochemistry. 2008 May;69(7):1507-16. doi: 10.1016/j.phytochem.2008.01.022. Epub 2008 Mar 14.
Many plants produce cyanogenic glucosides as part of their chemical defense. They are alpha-hydroxynitrile glucosides, which release toxic hydrogen cyanide (HCN) upon cleavage by endogenous plant beta-glucosidases. In addition to cyanogenic glucosides, several plant species produce beta- and gamma-hydroxynitrile glucosides. These do not release HCN upon hydrolysis by beta-glucosidases and little is known about their biosynthesis and biological significance. We have isolated three beta-hydroxynitrile glucosides, namely (2Z)-2-(beta-D-glucopyranosyloxy)but-2-enenitrile and (2R,3R)- and (2R,3S)-2-methyl-3-(beta-D-glucopyranosyloxy)butanenitrile, from leaves of Ribesuva-crispa. These compounds have not been identified previously. We show that in several species of the genera Ribes, Rhodiola and Lotus, these beta-hydroxynitrile glucosides co-occur with the L-isoleucine-derived hydroxynitrile glucosides, lotaustralin (alpha-hydroxynitrile glucoside), rhodiocyanosides A (gamma-hydroxynitrile glucoside) and D (beta-hydroxynitrile glucoside) and in some cases with sarmentosin (a hydroxylated rhodiocyanoside A).
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Other Natural Compounds Products

CAS 123621-00-1 Clerosterol glucoside

Clerosterol glucoside
(CAS: 123621-00-1)

Clerosterol glucoside isolated from the fresh fruits of Momordica charantia L.

CAS 26296-50-4 Ficaprenol 11

Ficaprenol 11
(CAS: 26296-50-4)

Ficaprenol 11 isolated from the herbs of Artocarpus heterophyllus.

Thevetin B
(CAS: 27127-79-3)

Thevetin B isolated from the herbs of Thevetia peruviana.

CAS 19083-00-2 Gracillin

(CAS: 19083-00-2)

Gracillin is a natural steroid isolated from the roots of Dioscorea opposita Thunb. Gracillin shows anti-tumor activity which can induce cell cycle arrest, oxid...


(CAS: 474-62-4)

Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. It is poorly absorbed in humans and competitively inhibits the absorption of c...

CAS 98665-65-7 Dregeoside Da1

Dregeoside Da1
(CAS: 98665-65-7)

Dregeoside Da1 is a natural steroid found in the herbs of Dregea volubilis.

(CAS: 145033-48-3)

Digalactosyldiacylglycerol is a natural compound found in several plants.

CAS 177602-14-1 Glycerol 1-(26-hydroxyhexacosanoate)

Glycerol 1-(26-hydroxyhexacosanoate)
(CAS: 177602-14-1)

Glycerol 1-(26-hydroxyhexacosanoate) comes from the herbs of Isodon sculponeata

(CAS: 122475-42-7)

4-O-(3-nitropropanoyl)corollin is a natural compound found in several plants.

CAS 90-64-2 DL-Mandelic acid

DL-Mandelic acid
(CAS: 90-64-2)

Mandelic acid was first discovered while heating amygdalin isolated from bitter almonds. Mandelic acid is used to treat urinary tract infections for its antibac...

CAS 113681-11-1 3-(Hydroxymethyl)cyclopentanone

(CAS: 113681-11-1)

3-(Hydroxymethyl)cyclopentanone isolated from the herb of Alangium chinese.

CAS 1072-93-1 Epigoitrin

(CAS: 1072-93-1)

Epigoitrin isolated from the root of Strobilanthes cusia (Nees) Ktze.

CAS 33457-62-4 Alnustone

(CAS: 33457-62-4)

Alnustone can be found in the seeds of Alpinia katsumadai Hayata.

CAS 22798-98-7 Ecdysterone 2,3:20,22-diacetonide

Ecdysterone 2,3:20,22-diacetonide
(CAS: 22798-98-7)

Ecdysterone 2,3:20,22-diacetonide isolated from the roots of Cyanotis arachnoidea C. B. Clarke.

CAS 112244-29-8 Stigmastane-3,6-diol

(CAS: 112244-29-8)

Stigmastane-3,6-diol isolated from the fruits of Trichosanthes kirilowii.

CAS 63139-16-2 Withanolide S

Withanolide S
(CAS: 63139-16-2)

Withanolide S is a steroid isolated from Physali alkekengi.

CAS 857897-01-9 11,12-Di-O-acetyltenacigenin B

11,12-Di-O-acetyltenacigenin B
(CAS: 857897-01-9)

11,12-Di-O-acetyltenacigenin B is a natural steroid found in the herbs of Marsdenia tenacissima.

Chemical Structure

CAS 71933-54-5 Sarmentosin

Quick Inquiry

Verification code

Featured Items