SAR156497 - CAS 1256137-14-0
Catalog number: 1256137-14-0
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C27H24N4O4
Molecular Weight:
468.5
COA:
Inquire
Targets:
Aurora Kinase
Description:
SAR156497 is a selective Aurora A, B and C inhibitor with in vitro and in vivo efficacy IC50 value is 0.5 nM for Aurora A; 1.0 nM for Aurora B (incenp) and 3.0 nM for Aurora C (incenp). In vitro, SAR156497 shows very good antiproliferative activity on a large panel of tumor cell lines.
Purity:
98%
Appearance:
Powder
Synonyms:
SAR156497; SAR156497; SAR 156497.
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
anti-tumor
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChI:
InChI=1S/C27H24N4O4/c1-2-34-26(33)25-24-17(14-28-25)22(23-20(29-24)11-6-12-21(23)32)15-7-5-8-16(13-15)35-27-30-18-9-3-4-10-19(18)31-27/h3-5,7-10,13-14,22,28-29H,2,6,11-12H2,1H3,(H,30,31)/t22-/m0/s1
Canonical SMILES:
O=C1CCCC2=C1[C@@H](C3=CC(OC4=NC5=C(C=CC=C5)N4)=CC=C3)C6=CNC(C(OCC)=O)=C6N2
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