|Description||S4 is a high affinity and selective carbonic anhydrase CA IX and CA XII inhibitor (Ki = 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively). S4 has been shown to inhibit migration and proliferation of breast cancer cells in in vitro assays. S4 inhibits lung metastasis in mice bearing breast tumor xenografts, without affecting primary tumor.|
|Brife Description||CA IX and CA XII inhibitor|
|Purity||≥99% by HPLC|
|Synonyms||4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate; CAIX Inhibitor S4|
SLC-0111, also known as U-104, MST-104 and NSC 213841, is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA I...
S4 is a high affinity and selective carbonic anhydrase CA IX and CA XII inhibitor (Ki = 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively). S4 has be...
Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.
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