(S)-PFI 2 hydrochloride - CAS 1627607-88-8
Category: Inhibitor
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Molecular Formula:
C23H25F4N3O3S.HCl
Molecular Weight:
535.98
COA:
Inquire
Targets:
Others
Description:
(S)-PFI 2 hydrochloride, a negative control of (R)-PFI 2 hydrochloride which a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM), shows 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer.
Purity:
≥97% by HPLC
Related CAS:
1627607-87-7
Synonyms:
(S)-PFI 2 hydrochloride; (S)-PFI2 hydrochloride; (S)-PFI-2 hydrochloride; (1S)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl]1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
ZADKZNVAJGEFLC-BOXHHOBZSA-N
InChI:
InChI=1S/C23H25F4N3O3S.ClH/c24-20-13-18(12-16-6-7-28-14-19(16)20)34(32,33)29-21(22(31)30-8-1-2-9-30)11-15-4-3-5-17(10-15)23(25,26)27;/h3-5,10,12-13,21,28-29H,1-2,6-9,11,14H2;1H/t21-;/m0./s1
Canonical SMILES:
C1CCN(C1)C(=O)C(CC2=CC(=CC=C2)C(F)(F)F)NS(=O)(=O)C3=CC(=C4CNCCC4=C3)F.Cl
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CAS 1627607-88-8 (S)-PFI 2 hydrochloride

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