|Description||A major active metabolite of Buspirone and a 5-HT1A partial agonist. In comparison with the (R)-enantiomer, (S)-6-Hydroxybuspirone hydrochloride is cleared more slowly from blood and has lower affinity and selectivity for the 5HT1A receptor.|
|Brife Description||5-HT1A partial agonist|
|Synonyms||BMS 442606 hydrochloride; (10S)-10-hydroxy-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride|
Org 37684 is a 5-HT2C receptor agonist.
Pimavanserin is a potent and selective 5-HT2A receptor inverse agonist used in the treatment of Parkinson’s disease psychosis.
AS 19 has been found to be a potent SR-7 agonist and could probably enhance memory consolidation.
ATC 0175 hydrochloride
The hydrochloride salt form of ATC 0175, which has been found to be a MCHR1, SR-1A and SR-2B inhibitor and probably show anxiolytic and antidepressant activitie...
LY 426965 dihydrochloride is a potent and selective 5-HT1A antagonist that is more active than its opposite enantiomer (R)-(-)-LY 426965.
GR 46611 is a 5-HT1D receptor agonist that may be beneficial for the treatment of migraine. 5-HT1D acts on the central nervous system.
Eplivanserin hemifumarate is a potent and selective 5-HT2A antagonist (IC50 = 5.8 and 120 and >100 nM for 5-HT2A, 5-HT2B and 5-HT2C, respectively) with no activ...
The maleic acid salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome.