(S)-6-Hydroxybuspirone - CAS 477930-31-7
Catalog number: 477930-31-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C21H31N5O3
Molecular Weight:
401.5
COA:
Inquire
Targets:
5-HT Receptor
Description:
(S)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the (S)-enantiomer; while (S)-Enantiomer has advantage of being cleared more slowly from blood compared to the (R)-enantiomer
Purity:
≥98%
Appearance:
Solid powder
Synonyms:
BMS-442606; 8-Azaspiro(4.5)decane-7,9-dione, 6-hydroxy-8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, (6S)-;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
5-HT1A partial agonist
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
KOZNAHJIJGCFJJ-GOSISDBHSA-N
InChI:
1S/C21H31N5O3/c27-17-16-21(6-1-2-7-21)18(28)19(29)26(17)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9,18,28H,1-4,6-7,10-16H2/t18-/m1/s1
Canonical SMILES:
c1cnc(nc1)N2CCN(CC2)CCCCN3C(=O)CC4(CCCC4)[C@@H](C3=O)O
Current Developer:
Bristol-Myers Squibb
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related 5-HT Receptor Products


CAS 845861-49-6 2-Methyl-5-hydroxytryptamine hydrochloride

2-Methyl-5-hydroxytryptamine hydrochlori
(CAS: 845861-49-6)

2-Methyl-5-hydroxytryptamine hydrochloride is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). It affects the gut functions including secret...

CAS 144734-36-1 4F 4PP oxalate

4F 4PP oxalate
(CAS: 144734-36-1)

4F 4PP oxalate is a selective 5-HT2A antagonist with almost as high affinity (Ki = 5.3 nM) as ketanserin but with a much lower affinity for 5-HT2C sites (Ki = 6...

CAS 607742-69-8 SB742457

SB742457
(CAS: 607742-69-8)

SB742457 is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.It was under development by GlaxoSmithKline f...

CAS 740873-06-7 Naluzotan

Naluzotan
(CAS: 740873-06-7)

Naluzotan is a selective 5-HT1A receptor partial agonist under the development of EPIX Pharmaceuticals. It is a serotonergic drug for the treatment of generaliz...

CAS 5189-11-7 Pizotifen Malate

Pizotifen Malate
(CAS: 5189-11-7)

Pizotifen Malate is a benzocycloheptane based agent used for recurrent migraine headaches.

CAS 82752-99-6 Nefazodone hydrochloride

Nefazodone hydrochloride
(CAS: 82752-99-6)

Nefazodone hydrochloride is a selective serotonin 5-HT2 receptor antagonist. It is used as an antidepressant that shows no cardiac toxicity or anticholinergic a...

CAS 148688-01-1 SB 204070

SB 204070
(CAS: 148688-01-1)

SB 204070 is a potent and selective 5-HT4 receptor antagonist (pIC50 = 10.1), displaying >5000-fold selectivity over 5-HT1A, 5-HT1D, 5-HT1E, 5-HT2A, 5-HT2C, and...

CAS 158876-82-5 Rupatadine

Rupatadine
(CAS: 158876-82-5)

Rupatadine, with the potential to treat allergic rhinitis and urticaria, is a potent and long-lasting dual antagonist of PAF/H1. in vitro: Without affecting con...

Quick Inquiry

Verification code

Featured Items