|Description||(S)-4-Carboxyphenylglycine has been found to be a competitive group I metabotropic glutamate receptor antagonist(S)-4-Carboxyphenylglycine has been found to be a competitive group I metabotropic glutamate receptor antagonist and selective for mGluR1.|
|Purity||≥99% by HPLC|
|Synonyms||(S)-4C-PG; (αS)-α-Amino-4-carboxybenzeneacetic Acid|
YM 298198 dihydrochloride
YM 298198 dihydrochloride is a selective mGluR-1 antagonist. In vivo, YM 298198 exhibits an antinociceptive effect in hyperalgesic mice.
O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of L-carnitine that transports fatty acids into the mitochondria. It was demonstrated that exhibits a...
The hydrochloride salt form of ACDPP, which has been found to be a mGluR-5 antagonist.
LSN 2463359 is an allosteric modulator at the mGlu5 receptor with EC50 value of 24 nM. It is brain penetrant and can reverse learning deficits in a rat model of...
YM 202074 is a high affinity and selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM 202074 binds to an allosteric site of the rat mGlu1 rec...
BMT-145027 is a potent mGluR5 PAM without inherent agonist activity with an EC50 of 47 nM. BMT-145027 is a non-MPEP site PAM to demonstrate in vivo efficacy.
LY 354740 is a selective group II mGlu receptors agonist with EC50 values are 5.1 and 24.3 nM at mGlu2 and mGlu3 receptors. It shows antianxiety and antiaddicti...
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibiting no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.