|Description||(S)-3-Hydroxyphenylglycine is an agonist at group I metabotropic glutamate receptors (mGlu1) with no effect at mGlu2 or mGlu4.|
|Brife Description||mGlu1 receptor agonist|
|Purity||≥99% by HPLC|
LY 354740 is a selective group II mGlu receptors agonist with EC50 values are 5.1 and 24.3 nM at mGlu2 and mGlu3 receptors. It shows antianxiety and antiaddicti...
(RS)-APICA has been found to be a group II metabotropic glutamate receptor antagonist and could increase extracellular glutamate concentrations and possesses un...
TCN238 is an orally available, brain penetrant and positive allosteric mGlu4 receptor modulator (EC50= 1 μM) with 30-fold selectivity over mGluR5 using human re...
ML-289 is a negative allosteric modulator of mGlu3 with IC50 value of 0.66 μM. It displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.1.
VU 0409106 is a potent and selective mGlu5 negative allosteric modulator (IC50 = 49 nM for human mGlu5) with selectivity over a panel of GPCRs and ion channels....
HexylHIBO is a Group I mGlu receptor antagonist (Ki = 140 and 110 μM at mGlu1a and mGlu5a receptors, respectively). HexylHIBO was shown to decrease sEPSCs in ra...
Desmethyl-YM 298198 is a derivative of YM 298198, a selective antagonist of mGlu1.
(S)-4C3H-PG has been found to be a competitive GluR1 glutamate receptor antagonist as well as metabotropic GluR2/3 glutamate receptor agonist.