|Description||(S)-3-Hydroxyphenylglycine is an agonist at group I metabotropic glutamate receptors (mGlu1) with no effect at mGlu2 or mGlu4.|
|Brife Description||mGlu1 receptor agonist|
|Purity||≥99% by HPLC|
CDPPB is a positive allosteric modulator of mGlu5 receptor (EC50 = 10 and 20 nM for human and rat receptors, respectively). Study shows that CDPPB has a therape...
LY 379268 is a group II mGlu receptor agonist with EC50 values of 2.69 and 4.48 nM for hmGlu2 and hmGlu3. Some research shows that LY379268 can attenuate cocain...
(S)-4C3H-PG has been found to be a competitive GluR1 glutamate receptor antagonist as well as metabotropic GluR2/3 glutamate receptor agonist.
Cinnabarinic acid is a kynurenine pathway metabolite of tryptophan and is produced by the oxidation of 3-Hydroxyanthranilic acid. It is a metabotropic glutamate...
MAP4 is a selective group III metabotropic glutamate receptor (mGluR) antagonist in some electrophysiological systems. It acts as a group II/group III agonist i...
VU 0360223 is a potent mGlu5 negative allosteric modulator (IC50 = 61 nM) that has no activity at mGlu1-4 and mGlu7-8.
LY 354740 is a selective group II mGlu receptors agonist with EC50 values are 5.1 and 24.3 nM at mGlu2 and mGlu3 receptors. It shows antianxiety and antiaddicti...
ACPT-II has been found to be a mGluR antagonist and could probably exhibit neuroprotective effects.