|Description||(S)-3-Carboxy-4-hydroxyphenylglycine has been found to be a mixed group II mGlu agonist as well as group I metabotropic glutamate receptor antagonist.|
|Purity||≥98% by HPLC|
(1S,3R)-ACPD, an isomer of (±)-trans-ACPD, has been found to be an agonist of mGluRs.
(RS)-3,5-DHPG is a group I metabotropic glutamate receptor agonist with selectivity for both mGluR1 and mGluR5. S-enantiomer (S)-3,5-DHPG is the active form.
LSN 2463359 is an allosteric modulator at the mGlu5 receptor with EC50 value of 24 nM. It is brain penetrant and can reverse learning deficits in a rat model of...
YM 230888 is a selective mGlu1 antagonist (Ki = 13 nM) that inhibits mGlu1-mediated inositol phosphate production in rat cerebellar granule cells (IC50 = 13 nM)...
RG7090 is a negative modulator of metabotropic glutamate receptor subtype 5 (mGluR5; GRM5).
DCG IV is a potent group II mGluR agonist and a presynaptic depressant.
The hydrochloride salt form of ACDPP, which has been found to be a mGluR-5 antagonist.
L-Cysteinesulfinic acid is an agonist of mGlu1a and mGlu5a subtypes expressed in clonal RGT cell lines and an agonist of NMDA. It is used to probe conformationa...