S 18986 - CAS 175340-20-2
Category: Inhibitor
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Molecular Formula:
C10H12N2O2S
Molecular Weight:
224.28
COA:
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Targets:
AMPAR
Description:
S 18986 is a positive allosteric modulator of AMPA receptors that enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices. S 18986 exhibits neuroprotective and cognitive-enhancing properties in rodent behavioral models.
Brife Description:
positive allosteric modulator of AMPA receptors
Purity:
≥98% by HPLC
Synonyms:
S18986; S-18986; S 18986; S18986-1; S-18986-1; S 18986-1. (3aS)-2,3,3a,4-Tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine-5,5-dioxide
MSDS:
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InChIKey:
MNTIJYGEITVWHU-SNVBAGLBSA-N
InChI:
InChI=1S/C10H12N2O2S/c13-15(14)9-5-2-1-4-8(9)12-7-3-6-10(12)11-15/h1-2,4-5,10-11H,3,6-7H2/t10-/m1/s1
Canonical SMILES:
C1CC2NS(=O)(=O)C3=CC=CC=C3N2C1
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CAS 175340-20-2 S 18986

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