S 12 - CAS 258264-62-9
Category: Inhibitor
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Molecular Formula:
C17H12BrNO5
Molecular Weight:
390.18
COA:
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Targets:
Others
Description:
S 12 is a survivin inhibitor that alters spindle formation, resulting in mitotic arrest (by disrupting metaphase at the G2/M stage) and apoptosis. It inhibits cell proliferation and tumor growth independently of p53 status.
Brife Description:
survivin inhibitor
Purity:
99%
Synonyms:
S12; NSC201630; MLS000029787; SMR000010018; S 12; NSC 201630; MLS 000029787; SMR 000010018; S-12; NSC-201630; MLS-000029787; SMR-000010018; 3-[2-(1,3-benzodioxol-5-yl)-2-oxoethyl]-5-bromo-3-hydroxy-1,3-dihydro-2H-indol-2-one
MSDS:
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Application:
antitumor agent
InChIKey:
WFYHAKOLBICHEZ-UHFFFAOYSA-N
InChI:
InChI=1S/C17H12BrNO5/c18-10-2-3-12-11(6-10)17(22,16(21)19-12)7-13(20)9-1-4-14-15(5-9)24-8-23-14/h1-6,22H,7-8H2,(H,19,21)
Canonical SMILES:
C1OC2=C(O1)C=C(C=C2)C(=O)CC3(C4=C(C=CC(=C4)Br)NC3=O)O
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Chemical Structure

CAS 258264-62-9 S 12

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