|Description||10-Hydroxycamptothecin inhibits the growth of BT-20 and MDA-231 cell with IC50 of 34.3 nM and 7.27 nM, respectively, more potently than camptothecin (CPT) with IC50 of >500 nM.|
Piperidolate is a tertiary amine antimuscarinic. It is similar to atropine. It is mainly used in the smooth muscle spasm of the gastrointestinal tract and inhib...
Catalpol can be extracted from the herb of Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey. It primary function is to stimulate the production of adrenal...
Metrizamide is a X-ray contrast agent related to Metrizoic Acid, used as a diagnostic aid (radiopaque medium).
HTS01037, a high-affinity ligand of adipocyte fatty acid binding protein (A-FABP/aP2) (Ki = 0.67 μM), and is a competitive antagonist of protein-protein interac...
Notoginsenoside Ft1, a new saponin solated from the leaves of P. notoginseng, as a stimulator of angiogenesis it is more potent compared with other bioactive sa...
Cgp 38560 is a potent renin inhibitor and it can induce a dose-dependent decrease in angiotensin II and plasma renin activity and a long-lasting and dose-depend...
TAK-683 is an investigational peptide derivative of metastin under the development of Millennium. It is a KISS1R protein agonist. Phase I development for prosta...
Dimesna is a synthetic derivative of dithio-ethane sulfonate with uroprotective properties. In the kidney, dimesna undergoes reduction to the free thiol compoun...
FR-182980, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hypercholesterolaemia.
Troxipide is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of p...
DL-Glutamine is an unnatural amino acid and could be used for general biochemical research and drug synthesis.
Taurocholic Acid Sodium Salt Hydrate
Choleretic; Its sodium salt is a bile salt formed in the liver by conjugation of cholic acid with taurine that is involved in the emulsification of lipids used ...
Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it...
Ibandronate sodium is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associa...
(Z)-MDL 105519 is the inactive isoform of MDL 105519 which is a high affinity NMDA glutamate receptor antagonist at the glycine site.
This active molecular has a para-benzoquinone structure and was developed for inherited mitochondrial diseases base on vitamin E. The mechanism of action of Vat...
Gestrinone, also called as R2323, is a synthetic steroid hormone occasionally used to treat endometriosis and it inhibits leiomyoma cells (IC50= 43.67 μM).
A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpe...
Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.
Acebutolol is a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity as a beta blocker for the treatment of hypertension and arrhythmi...