RU-SKI 43 hydrochloride
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C22H30N2O2S.HCl
Molecular Weight:
423.01
COA:
Inquire
Targets:
Hedgehog
Description:
RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase) (IC50 = 0.85 µM). RU-SKI 43 is cell-permeable and inhibits both autocrine and paracrine Shh-induced activation of Gli-mediated transcription. It attenuates pancreatic cancer cell proliferation.
Purity:
≥98% by HPLC
Synonyms:
2-((2-Methylbutyl)amino)-1-(4-((3-methylphenoxy)methyl-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanone hydrochloride
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
JBBKLHJLHRGJSQ-UHFFFAOYSA-N
InChI:
InChI=1S/C22H30N2O2S.ClH/c1-4-16(2)13-23-14-22(25)24-10-8-21-19(9-11-27-21)20(24)15-26-18-7-5-6-17(3)12-18;/h5-7,9,11-12,16,20,23H,4,8,10,13-15H2,1-3H3;1H
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