|Description||RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.|
|Synonyms||RU-SKI 43; RU SKI 43; RUSKI43|
RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.
Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduct...
RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase) (IC50 = 0.85 µM). RU-SKI 43 is cell-permeable and inhibits both autocrine and paracrin...
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from th...
NL-103, a nicotinamide derivative, has been found to be an inhibitor of both histone deacetylases and hedgehog pathway. It was found to exhibit activity in decr...
Vismodegib (GDC-0449) is a potent, novel and specific inhibitor of hedgehog with IC50 of 3 nM and also inhibitor of P-gp with IC50 of 3.0 μM.
AZ 12080282 dihydrochloride is the dihydrochloride salt of AZ 12080282, which is a novel hedgehog antagonist and inhibits towards the SMO receptor affecting emb...
Ciliobrevin A is a Hedgehog (HH) pathway inhibitor and is a key signaling molecule in HH pathway. It blocked HH pathway activation by SAG, decreased Smo ciliary...