|Description||RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.|
U 18666A is a cell-permeable and amphiphilic amino-steroid that inhibits cholesterol synthesis and cellular transport via the suppression of 2,3-oxidosqualene-l...
Ciliobrevin A is a Hedgehog (HH) pathway inhibitor and is a key signaling molecule in HH pathway. It blocked HH pathway activation by SAG, decreased Smo ciliary...
SAG 21k is a potent, brain penetrating and orally available activator of Hedgehog signaling (EC50 = 0.4 nM).
Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduct...
RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.
AZ 12080282 dihydrochloride is the dihydrochloride salt of AZ 12080282, which is a novel hedgehog antagonist and inhibits towards the SMO receptor affecting emb...
HPI 1 is a hedgehog (Hh) signaling inhibitor that blocks Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 = 1.5, 1.5,...
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from th...