|Description||RS 25344 hydrochloride is a potent and selective inhibitor of four cloned isoforms of PDE4 (A, B, C and D) and phosphorylated PDE4D (IC50= 0.28, > 100, 160 and 330 nM at PDE4, PDE1, PDE2 and PDE3 respectively). It has been shown to inhibit eosinophil chemotaxis and increase progressive motility of spermatozoa in vitro.|
|Purity||≥98% by HPLC|
|Related CAS||152814-89-6 (free base)|
|Synonyms||1-(3-Nitrophenyl)-3-(4-pyridinylmethyl)-pyrido[2,3-d]pyrimidine-2,3-(1H,3H)-dione hydrochloride; RS-25344 HCl; RS 25344 HCl; RS25344 HCl|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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