|Molecular Formula||C20H24N10O12P2S2 (free acid)|
|Molecular Weight||722.6 (free acid)|
|Description||Rp,Rp-c-diGMPSS is an analogue of c-diGMP, the bacterial second messenger, with improved stability. It can be used to study ligand-receptor interactions.|
|Purity||≥ 95% by HPLC|
|Synonyms||Cyclic diguanosine monophosphorodithioate, Rp- isomers, sodium salt|
2'-TAMRA-AEC-cGMP is a fluorescent cGMP analogue (λexc555 nm, λem580 nm) that can be used for phosphodiesterase studies.
8-AHT-cGMP is a ligand in affinity chromatography and can be modified with fluorophores or other markers.
Sp-8-BnT-2'-O-Me-cAMPS is the most potent 2'-substituted activator of Epac2. In human osteosarcoma U2OS cell lines expressing Epac1 or Epac2, Sp-8-BnT-2'-O-Me-c...
c-di-2'-dAMP is an analogue of c-diAMP, the bacterial second messenger.
8-APT-cGMP is an isozyme-selective stimulator of cGMP-dependent protein kinase I a with a prenference for type I a over I by a factor of 200.
c[A(2',5')pS[Sp]-A(3',5')pS[Rp]] is asyntheticdi-thiophosphate analogue of c[A(2',5')pA(3',5')p] with higher stability resisting degradation by phosphodiesteras...
2-Cl-ATP is an agonist of P2Y purinoceptor that inhibits soluble guanylate cyclase.
8-AEA-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucl...
EtOH-NH-Agarose is the agarose gel without nucleotide immobilized on it, which can be used as negative control in affinity chromatography experiments.
6-AH-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminohexyl spacer which can be used in affinity chromatography of cyclic nucleotide-...
Sp-8-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatogra...
Rp-cGMPS is an inhibitor of protein kinase G Iα with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Both membrane permeabil...
8-OH-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It can be used in patc...
Rp-8-CPT-cAMPS is an analog of Rp-cAMPS and a competitive inhibitor of protein kinase A type I and II (cAMP antagonist). It effects against mammalian cyclic nuc...