|Molecular Formula||C10H11N5O6PS · Na|
|Description||Rp-cGMPS is an inhibitor of protein kinase G Iα with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Both membrane permeability and kinase specificity of Rp-cGMPS are low.|
|Purity||≥ 99% by HPLC|
|Synonyms||Guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt|
Sp-2'-AHC-cAMPS is a PDE-stable analogue of cAMP used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
6-MBC-cAMP is a selective activator of protein kinase A, the cAMP agonist, which has a preference for the A site of cAK II. It can be active to type II in combi...
2',2''-Di-O-Me-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
ara-cAMP is an analogue of cAMP, the second messenger. It is commonly used in receptor mapping studies and negative controls.
8-pHPT-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has superior lipo...
c-di-2'-d-2''-O-Me-AMP is an analogue of c-diAMP, the bacterial second messenger.
DB-cAMP is a membrane-permeant activator of protein kinase A, the cAMP agonist.
Rp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and...
Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to ...
8-Br-cGMP-AM is a precursor of 8-Br-cGMP, the PKG activator. The polar active analogue is released after the metabolism of 8-Br-cGMP-AM by esterases.
Rp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG inhibitor Rp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chrom...
Rp-8-CPT-cAMPS is an analog of Rp-cAMPS and a competitive inhibitor of protein kinase A type I and II (cAMP antagonist). It effects against mammalian cyclic nuc...
1-NO-cAMP is a polar cAMP analogue used for receptor mapping studies.
c-(ApIp) is a hybrid cyclic dinucleotide consisting of a 5'-AMP and a 5'-IMP unit.
2'-APNC-cAMP is an analogue of cAMP with higher solubility in water, which can be used as a ligand in affinity chromatography and be modified with fluorophores ...
c-diAMP was recognized as a second messenger for signalling DNA integrity in Bacillus subtilisduring sporulation, and an additional purine-based signalling nucl...
Rp,Sp-c-diAMPSS is an analogue of c-diAMP, the bacterial second messenger, which has higher stability. It can be used to study ligand-receptor interactions.