|Molecular Formula||C10H11N5O6PS · Na|
|Description||Rp-cGMPS is an inhibitor of protein kinase G Iα with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Both membrane permeability and kinase specificity of Rp-cGMPS are low.|
|Purity||≥ 99% by HPLC|
|Synonyms||Guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt|
8-AHA-cAMP is a selective cAMP analogue preferring site B of R I of cAMP-dependent protein kinase. It can be active to site A of R I and site B of R II combinin...
Rp-2'-AEC-cAMPS is an analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures su...
c[G(2',5')pG(2',5')p] is a cyclic dinucleotide analogue of c-diGMP, the bacterial second messenger.
c-diAMP was recognized as a second messenger for signalling DNA integrity in Bacillus subtilisduring sporulation, and an additional purine-based signalling nucl...
Rp-2'-AEC-cAMPS-Agarose is the protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chroma...
8-AET-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores or other markers.
2'-APNC-cAMP is an analogue of cAMP with higher solubility in water, which can be used as a ligand in affinity chromatography and be modified with fluorophores ...
Rp-8-Br-PET-cGMPS is a selective inhibitor of cGMP-dependent protein kinase I a and I β and of retinal cGMP-gated ion channels. It effects against mammalian cyc...
Sp-2'-O-MB-cAMPS is a precursor ofSp-cAMPS, a PDE-resistant stimulator of protein kinase A. Sp-cAMPS and butyrate are released after the metabolism of Sp-2'-O-M...
Rp-cCMPS is a PDE-resistant cCMP, the potential second messenger, which inhibits cCMP-binding proteins.
8-Br-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used for binding studies and precursor for further modifications with space...
cAMP-Bn is a precursor of cAMP, the second messenger. The polar cAMP is released after cAMP-Bn is hydrolyzed to produce an elevated cAMP level for a prolonged p...
Sp-c-diAMPS is an analogue of c-diAMP, the bacterial second messenger.
Sp-8-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatogra...
Rp,Sp-c-diGMPSS is an analogue of c-diGMP, the bacterial second messenger, with improved stability. It can be used to study ligand-receptor interactions.
8-AHA-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer, which can...