|Molecular Formula||C10H11N5O6PS · Na|
|Description||Rp-cGMPS is an inhibitor of protein kinase G Iα with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Both membrane permeability and kinase specificity of Rp-cGMPS are low.|
|Purity||≥ 99% by HPLC|
|Synonyms||Guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt|
c[8-Br-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger, which can be used for binding studies and...
2'-O-MS-cAMP is a cAMP analogue used for coupling of ligands including proteins for ELISA.
2'-AHC-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling...
1-NH2-cGMP is a selective cGMP analogue that has a higher affinity of site A in cGK, and it is commonly used for synergism studies.
Sp-2-AHA-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and ot...
Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I ...
Sp-cGMPS is a resistant stimulator of cGMP-dependent protein kinases.
Sp-5,6-DCl-cBIMPS is a selective stimulator of cAMP- dependent protein kinases preferrring site B of type II isozyme. It is superior to dibutyryl cAMP or 8-CPT-...
8-AET-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores or other markers.
2',2''-Di-O-Me-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which selectively binds the c-diGMP class II riboswitch. It can be used to dis...
2'-O-Me-cAMP is a polar analogue of cAMP that cannot activate protein kinase A.
c-diAMP was recognized as a second messenger for signalling DNA integrity in Bacillus subtilisduring sporulation, and an additional purine-based signalling nucl...
6-AE-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethyl spacer which can be used in affinity chromatography of cyclic nucleotide-...
8-MBT-cAMP is a cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
8-AET-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activ...
Rp-8-OH-cAMPS is a polar analogue of Rp-cAMPS, the protein kinase A inhibitor, used for the study of extracellular cAMP receptors. It inhibits mammalian cyclic ...
8-pCPT-cGMP is a selective activator of cGMP-dependent protein kinase type I α and type II, as well as of cGMP-gated ion channels. It has higher membrane permea...
8-Br-cGMP-AM is a precursor of 8-Br-cGMP, the PKG activator. The polar active analogue is released after the metabolism of 8-Br-cGMP-AM by esterases.