|Molecular Formula||C18H14BrN5O6PS · Na|
|Description||Rp-8-Br-PET-cGMPS is a selective inhibitor of cGMP-dependent protein kinase I a and I β and of retinal cGMP-gated ion channels. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-8-pCPT-cGMPS, it is much more lipophilic and membrane-permeant.|
|Purity||≥ 99% by HPLC|
|Synonyms||8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt|
2',3'-cAMP is a positional isomer of 3',5'-cAMP that is produced by organ systems such as rat and mouse kidney and mouse brain through RNA degradation. When inj...
Sp-6-AH-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and oth...
Sp-6-Bnz-cAMPS is a selective and PDE-resistant stimulator of cAMP-dependent protein kinase, which can be used as an Epac-negative control.
2-Cl-cAMP is a selective cAMP analogue preferring the B sites of both protein kinase A type I and II.
Rp-2'-AHC-cAMPS-Agarose is the PDE-resistant protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in a...
Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is a...
Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases.
Sp-2'-AHC-cGMPS is a PDE-stable cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
2-AHA-cAMP is a ligand in affinity chromatography and can be modified with fluorophores and other markers.
c[G(2',5')pA(3',5')p] / 2'3'-cGAMP
c[G(2',5')pA(3',5')p] was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. ...
cCMP-AM is a membrane-permeant and metabolically activatable prodrug of cCMP, the potential further second messenger. cCMP is released after permeation and meta...
8-AHA-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activ...
8-Br-2'-O-Me-cGMP is an analogue of cGMP that does not activate both protein kinase G and Epac. It is often used as an inactive control versus 8-Br-cGMP.
2-ADOA-cAMP is a hydrophilic analogue of cAMP, which is used as a ligand in affinity chromatography and can be modified with fluorophores.
Rp-8-Br-2'-O-MB-cAMPS is a precursor of Rp-8-Br-cAMPS, the protein kinase A inhibitor. Rp-8-Br-cAMPS and butyrate are released after the metabolism of Rp-8-Br-2...