|Description||Ro 51 is a potent and selective dual antagonist of purinoceptor subtypes P2X3 and P2X2/3 (IC50 values are 2 and 5 nM for rP2X3 and hP2X2/3 respectively), without significant activity on other P2X receptors (IC50 values are > 10 μM for P2X1, P2X2, P2X4, P2X5, and P2X7). P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions making Ro 51 a potential option in the treatment of pain.|
|Purity||≥98% by HPLC|
|Synonyms||2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinyl]amino]-1,3-propanediol; Ro51; Ro-51; CHEMBL494161; 1050670-85-3; SCHEMBL4970553|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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