RN 9893 hydrochloride - CAS 1803003-68-0
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C21H23F3N4O5S.HCl
Molecular Weight:
536.95
COA:
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Targets:
TRP Channel
Description:
RN 9893 is a potent and selective antagonist of the Transient Receptor Potential ion channel TRPV4 (IC50= 320, 420 and 660 nM for mouse, human and rat channels, respectively), with >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets.
Purity:
≥99% by HPLC
Synonyms:
N-[4-[[4-(1-Methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)benzamide hydrochloride; RN9893 HCl; RN-9893 HCl; RN 9893 HCl; RN9893 Hydrochloride; RN-9893 Hydrochloride; RN 9893 Hydrochloride
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
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InChIKey:
ULUOUAGDTULBRZ-UHFFFAOYSA-N
InChI:
InChI=1S/C21H23F3N4O5S.ClH/c1-14(2)26-9-11-27(12-10-26)34(32,33)17-6-4-16(5-7-17)25-20(29)18-8-3-15(21(22,23)24)13-19(18)28(30)31;/h3-8,13-14H,9-12H2,1-2H3,(H,25,29);1H
Canonical SMILES:
CC(C)N1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=C(C=C(C=C3)C(F)(F)F)[N+](=O)[O-].Cl
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CAS 1803003-68-0 RN 9893 hydrochloride

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