RG14620 - CAS 136831-49-7
Catalog number: B0084-165138
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C14H8Cl2N2
Molecular Weight:
275.13
COA:
Inquire
Targets:
EGFR
Description:
RG14620 is a non-phenolic tyrphostin-class epidermal growth factor receptor (EGFR) inhibitor (IC50= 3 μM for HER 14 colony formation, and IC50= 1 pM for HER 14 DNA synthesis), with anti-proliferative effects on renal and bladder carcinoma cell lines.
Brife Description:
An epidermal growth factor receptor (EGFR) inhibitor
Synonyms:
(E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile; RG 14620; RG14620; RG-14620; TYRPHOSTIN RG 14620
Solubility:
DMSO: ≥ 26 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
418.2±45.0 ℃ at 760 Torr
Density:
1.355±0.06 g/cm3
InChIKey:
TYXIVBJQPBWBHO-QCDXTXTGSA-N
InChI:
1S/C14H8Cl2N2/c15-13-5-10(6-14(16)7-13)4-12(8-17)11-2-1-3-18-9-11/h1-7,9H/b12-4-
Canonical SMILES:
C1=CC(=CN=C1)C(=CC2=CC(=CC(=C2)Cl)Cl)C#N
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CAS 136831-49-7 RG14620

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