Retapamulin - CAS 224452-66-8
Catalog number: B1335-476353
Category: Metabolites
Molecular Formula:
C30H47NO4S
Molecular Weight:
517.8
COA:
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source\Analogue Sets:
Semi-synthetic | Pleuromutilin Analogue Set
Description:
Retapamulin is a semi-synthetic pleuromutilin prepared by reacting pleuromutilin tosylate with tropine-3-thiol. It exhibits a broad-spectrum antibiotic activity with no cross resistance to existing antibiotic classes. It is the first pleuromutilin approved for human use. It inhibits protein synthesis by binding to domain V of 23S rRNA.
Ordering Information
Catalog Number Size Price Stock Quantity
B1335-476353 1 g $168 In stock
B1335-476353 2.5 g $368 In stock
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Purity:
>99% by HPLC
Appearance:
White Solid
Synonyms:
Altabax; Altargo; SB-275833
Solubility:
Soluble in ethanol, methanol, DMF or DMSO. Moderate water solubility.
Storage:
Store at -20°C
MSDS:
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Melting Point:
127-129ºC
InChIKey:
STZYTFJPGGDRJD-FJJJPKKESA-N
InChI:
InChI=1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1
Canonical SMILES:
CC1CCC23CCC(=O)C2C1(C(CC(C(C3C)O)(C)C=C)OC(=O)CSC4CC5CCC(C4)N5C)C
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Chemical Structure

CAS 224452-66-8 Retapamulin

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