|Description||Radiocicol is an antifungal antibiotic. It inhibits heat Hsp90 activity by binding to the ATP-binding pocket, subsequently suppressing cell transformation induced by src, ras and mos. Represses estrogen receptor transcriptional activity and inhibits angiogenesis.|
|Brife Description||Radicicol is a Hsp90 inhibitor and also an antifungal antibiotic.|
|Appearance||White / yellow solid|
|Synonyms||KF58332; KF 58332; KF-58332; (1AR,2Z,4E,14R,15AR)-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE; [1AS-(1AR*,2Z,4E,14*,15AR*)]-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E]BENZOXACYC|
|Solubility||Ethanol: 25 mg/mL|
|Storage||Desiccate at -20°C|
|Melting Point||190-194 oC|
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