R916562 - CAS 1037798-41-6
Catalog number: B0084-267742
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C26H30ClN9S
Molecular Weight:
536.09
COA:
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Targets:
VEGFR
Description:
R916562, a diaminotriazole compound, is a potential and selective Axl/VEGF-R2 dual inhibitor with IC50s of 136 and 24 nM, respectively. R916562 showed activity comparable to the clinically approved tyrosine kinase inhibitor Sunitinib in mouse tumor xenograft models and the corneal micropocket angiogenesis model.
MSDS:
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Canonical SMILES:
NC1=NC(NC(C=C2)=CC=C2N3CCN([C@H]4[C@@H]5CC[C@@H](C5)C4)CC3)=NN1C6=NC(Cl)=NC7=C6SC=C7C
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