|Targets||Human dopamine-beta-hydroxylase, Bovine dopamine-beta-hydroxylase|
|Description||(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter|
|Synonyms||RS-25560-198 HCl; RS 25560 198 HCl|
CP 544326, also known as taprenepag, is a potent and selective EP(2) receptor agonist. Its EC50 value is 2.8 nM. It is the active acid metabolite of the prodrug...
Tonapofylline, a selective adenosine-1 receptor antagonist, has natriuretic effects and is able to maintain renal function, which can be beneficial to patients ...
Betrixaban is a long-acting anticoagulant used for the treatment of venous thromboembolism (VTE) caused by limited mobility or some other factors in adult patie...
CGP 71683 hydrochloride
CGP 71683 hydrochloride is a highly selective non-peptide antagonist of the NPY Y(5) receptor (IC50= 1.4 nM) with > 1000-fold selectivity over Y1 (IC50= 2765 nM...
PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR (Kis= 10.6 nM and 12.5 nM for mTOR and PI3Kα, respectively).
CP-810123 is a novel alpha 7 nAChR agonist with potential treatment for cognitive deficits associated with psychiatric or neurological conditions including schi...
The hydrochloride of Tanzisertib. Tanzisertib (CC-930) is a potent and selective JNK inhibitor which is potentially used for prevention and treatment of dermal ...
Ro 15-4513, a high affinity benzodiazepine ligand, acts as a competitive antagonist, and can therefore be an antidote to the acute impairment caused by alcohol....