|Description||(R)-(-)-N-Desmethyl-PK 11195 is a precursor to (R)-[N-methyl-11C]PK 11195 for PET studies and a radioligand precursor to the peripheral benzodiazepine antagonist (R)-[N-methyl-11C]PK 11195.|
|Synonyms||(R)-N-Desmethyl PK11195; (R)-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide|
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM.
SN-28049SN is a DNA intercalating drug that binds selectively to GC-rich DNA and shows curative activity against the Colon 38 adenocarcinoma in mice. SN 28049 h...
Org 12962 hydrochloride
Org 12962 hydrochloride is a 5-HT2C receptor agonist with pEC50 value of 7.01. It shows antiaversive effects in the anxiety models in rats.
6β-Naltrexol Hydrochloride is a neutral opioid antagonist, as a metabolite of Naltrexone, which is an opioid antagonist.
Losmapimod is a promising new agent against cardiovascular diseases. This drug works by inhibiting p38 MAP kinases, which play an important role in the developm...
CP-67804 enhances topoisomerase II-mediated DNA cleavage. It represent a novel class of topoisomerase II-targeted drugs which have potential as antineoplastic a...
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
(S)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the ...