|Description||(R)-(-)-LY 426965 dihydrochloride is a selective 5-HT1A antagonist that is less active than its opposite (S)-(+)-enantiomer LY 426965.|
|Brife Description||5-HT1A antagonist|
|Synonyms||(R)-(-)-LY 426965 dihydrochloride; (R)-(-)-LY426965 dihydrochloride; (R)-(-)-LY-426965 dihydrochloride; (2R)-1-cyclohexyl-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-methyl-2-phenylbutan-1-one dihydrochloride|
MDL 100151 is the racemic MDL 100907 and a selective 5-HT2A antagonist.
Lasmiditan is a high-affinity, highly selective 5-HT1F receptor agonist(Ki=2.1 nM) for the treatment of acute migraine.
Lu AE58054 is a selective and high affinity 5-HT6 receptor antagonist as promising treatment for cognitive disorders.
RS 67506 hydrochloride
RS 67506 hydrochloride is a potent and selective 5-HT4 partial agonist, with a pKi of 8.8 at 5-HT4 sites in guinea pig striatum, but < 6.0 at several other rece...
Risperidone is a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist.
2-Methyl-5-hydroxytryptamine hydrochloride is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). It affects the gut functions including secret...
1-Phenylbiguanide hydrochloride is a 5-HT3 receptor agonist.
LY 393558 is a 5-HT reuptake inhibitor with pIC50 value of 8.48. It is also a dual 5-HT1B/1D receptor antagonist with pKB values of 9.05 and 8.98 respectively.