|Description||(R)-BPO-27, the benzopyrimido-pyrrolo-oxazinedione, is a potent CFTR inhibitor (IC50= 4 nM) with low-nanomolar potency.|
|Brife Description||A potent CFTR inhibitor (IC50= 4 nM)|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||732.9±70.0 ℃ at 760 Torr|
Ataluren is an investigational new drug designed to enable the formation of a functioning protein in patients with genetic disorders due to a nonsense mutation....
BPO-27 racemate inhibited CFTR with IC50 ≈ 8 nM and had greatly improved in vitro metabolic stability and aqueous solubility compared to PPQ-102.
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(R)-BPO-27, the benzopyrimido-pyrrolo-oxazinedione, is a potent CFTR inhibitor (IC50= 4 nM) with low-nanomolar potency.
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