|Description||(R)-(-)-alpha-Methylhistamine dihydrobromide is a potent and high affinity histamine H3 agonist (KD = 50.3 nM) displaying > 200-fold selectivity over H4 receptors. It inhibits H3-mediated histamine synthesis and release in the CNS at nanomolar concentrations, and induces H4-mediated eosinophil shape change (EC50 = 66 nM).|
|Brife Description||histamine H3 agonist|
|Purity||≥99% by HPLC|
Ebrotidine(FI 3542), a competitive H2-receptor antagonist, has gastroprotective activity under the condition of gastric mucosal damage caused by some stress res...
The hydrochloride salt form of Dimaprit, which has been found to be a histamine H2 receptor agonist.
Epinastine is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is highly selective for ...
The dihydrochloride salt form of Mizolastine which is effective in the treatment of seasonal allergic rhinitis, perennial allergic rhinitis and other allergy sy...
Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
VUF 5681 dihydrobromide
VUF 5681 dihydrobromide is a potent histamine H3 receptor silent antagonist (pKi = 8.35).
Azelastine, a phthalazine derivative, is a potent, second-generation, selective, histamine antagonist used as a first line therapy of mild intermittent.
4-Methylhistamine dihydrochloride is a potent, high affinity H4 receptor agonist (Ki = 7 nM) that displays > 100-fold selectivity over other human histamine rec...