|Description||(R)-3,4-DCPG is an AMPA receptor antagonist with weak activity at NMDA receptors and no activity at kainate receptors.|
|Brife Description||AMPA receptor antagonist|
|Purity||≥96% by HPLC|
|Related CAS||176796-64-8 (racemic mixture)|
|Synonyms||(R)-3,4-Dicarboxyphenylglycine; 4-[(1R)-1-Amino-2-hydroxy-2-oxoethyl]phthalic acid|
S 18986 is a positive allosteric modulator of AMPA receptors that enhances (S)-AMPA-mediated noradrenaline release in rat hippocampal and frontal cortex slices....
NBQX disodium salt
The sodium salt form of NBQX, which has been found to be an AMPA receptor antagonist and could be used as neuroprotective as well as anticonvulsant agent.
GYKI-47261 is a non-competitive AMPA receptor antagonist (IC50 = 2.5 μM) and a CYP2E1 inducer. GYKI-47261 shows broad spectrum anticonvulsive activity and neuro...
Org-26576 is a positive allosteric modulator of AMPA receptor. Org-26576 increases the anteroventral and laterodorsal thalamus, cingulate cortex, dentate gyrus ...
LY3130481, a benzothiazol derivative, has been found to be the first AMPA receptor antagonist that could be probably effective in studies of epilepsy. It has ju...
Cyclothiazide has been found to be a subunit-specific inhibitor of GABAC receptors and could be used as a diuretic agent as well as antihypertensive agent.
SYM 2206 is a potent and noncompetitive AMPA receptor antagonist (IC50 = 2.8 μM ) that exhibits anticonvulsant activity in vivo. SYM 2206 acts allosterically at...
Kynurenic acid is a product of L-Tryptophan metabolism. It is a non-selective antagonist at NMDA and AMPA/kainate receptors. It could block kainic acid neurotox...