|Description||This active molecular also known as AC220 and AC010220, is developed as a new second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, ten fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Now Quizartinib is in Phase-III clinical trials in Acute myeloid leukaemia.|
|B0084-157290||100 mg||$199||In stock|
|Related CAS||1132827-21-4 (2HCl)|
|Synonyms||1-(5-(tert-butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea; AC220; AC 220; AC-220; AC010220; AC-010220; AC 010220; AC010220; Quizartinib|
|Solubility||Soluble in DMSO|
|Application||treatment of Acute myeloid leukaemia(AML).|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||Cancer Research UK; Cardiff University; Daiichi Sankyo Company; University of Texas M. D. Anderson Cancer Center|
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