|Description||Pyr3, a pyrazole derivative, is a selective antagonist of the TRP canonical 3 channel (TRPC3) which can function as a receptor-operated channel. It inhibits TRPC3-mediated Ca2+ influx with an IC50 value of 0.7 μM without effect on other TRPC members and suppresses activation of nuclear factor of activated T cells with an IC50 value of 0.05 μM.|
|Purity||≥98% by HPLC|
|Appearance||Off-White to Pale Yellow Solid|
|Synonyms||Pyr3; Pyr-3; Pyr 3; 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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